Thermo Fisher Scientific NCoR2 Polyclonal Antibody
Thermo Fisher Scientific의 NCoR2 Polyclonal Antibody는 인간 SMRT 단백질의 합성 펩타이드(aa 80–92)를 면역원으로 제작된 다클론 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the human SMRT protein corresponding to amino acids 80–92 (QELHLRPESHSYL) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560263 |
Product Specific Information
- Recommended positive controls: HBL100
Target Information
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily.
Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate.
Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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