Thermo Fisher Scientific FMO1 Polyclonal Antibody
Thermo Fisher Scientific의 FMO1 Polyclonal Antibody는 인간 FMO1 단백질을 인식하는 토끼 IgG 항체로, Western blot과 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 안정적인 신뢰성 있는 결과를 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 95–320 of Human FMO1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547508 |
Product Specific Information
- Recommended positive control: HepG2
- Predicted reactivity: Mouse (84%), Rat (84%), Dog (88%), Pig (88%), Rabbit (84%), Rhesus Monkey (98%), Bovine (85%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Metabolic N-oxidation of diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in humans, resulting in a small subpopulation with reduced TMA N-oxidation capacity (fish odor syndrome, Trimethylaminuria).
Three forms of the enzyme—FMO1 (fetal liver), FMO2 (adult liver), and FMO3—are encoded by genes clustered in the 1q23–q25 region.
Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyze oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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