
Thermo Fisher Scientific Chikungunya Virus E3 Recombinant Rabbit Monoclonal Antibody (HL2476)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:3,000
Immunocytochemistry (ICC/IF)
Assay-dependent
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rabbit / IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2476
Immunogen
Full length Chikungunya virus E3 recombinant protein.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3090471
Target Information
Chikungunya virus (CHIKV) belongs to the alphavirus family, the members of which have enveloped icosahedral capsids. The maturation process of alphaviruses involves proteolysis of some of the structural proteins before assembling with nucleocapsids to produce mature virions. E3 is implicated in serine-type endopeptidase activity. Cleavage of the alphavirus precursor glycoprotein p62 into the E2 and E3 glycoproteins before assembly with the nucleocapsid is the key to producing fusion-competent mature spikes on alphaviruses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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