Thermo Fisher Scientific MBTPS2 Polyclonal Antibody
Human MBTPS2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:20–1:50 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(40% glycerol) 완충액에 보관. 발달 및 콜레스테롤 항상성 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MBTPS2. Recombinant protein control fragment (Product # RP-92161) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643796 |
Product Specific Information
Immunogen sequence:
EVAEDSPAIG PRGLFVGDLV THLQDCPVTN VQDWNECLDT IAYEPQIGYC ISASTLQQLS FPVRAYKRLD GSTECCNNHS LTDVCFSYRN NFNKRLHTCL PARKAVEATQ VCRTNKDCKK SSSSSFCIIP SLETHTR
- Highest antigen sequence identity to the following orthologs:
- Mouse: 96%
- Rat: 98%
Target Information
This gene encodes an intramembrane zinc metalloprotease, which is essential in development.
This protease functions in signal protein activation involved in sterol control of transcription and the ER stress response.
Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome), which is linked to reduced cholesterol homeostasis and ER stress response.
[Provided by RefSeq, Aug 2009]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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