Thermo Fisher Scientific EPS15 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human EPS15. Recombinant protein control fragment (Product #RP-89543). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EPS15,uniProtId:P42566-1,ncbiNodeId:9606,antigenRange:657-798,antigenLength:896,antigenImageFileName:PA5-82353_EPS15_P42566-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82353_EPS15_P42566-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789512

Product Specific Information

Immunogen sequence: CFFRQSTDPF ATSSTDPFSA ANNSSITSVE TLKHNDPFAP GGTVVAASDS ATDPFASVFG NESFGGGFAD FSTLSKVNNE DPFRSATSSS VSNVVITKNV FEETSVKSED EPPALPPKIG TPTRPCPLPP GKRSINKLDS PD

Target Information

EPS15 is a ubiquitously expressed protein that is involved in cell growth regulation and may be involved in the regulation of mitogenic signals and control of cell proliferation. Phosphorylation of EPS15 on Tyrosine 849 upon DNA damage is involved in the internalization of EGFR. A chromosomal aberration involving EPS15 is also found in acute leukemias, resulting in a rogue activator protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.