Thermo Fisher Scientific Ataxin 7 Polyclonal Antibody
Rat Ataxin 7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 제공됩니다. 고순도 Affinity chromatography 정제 방식으로 제조되어 신뢰성 높은 연구용 데이터 확보에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of rat Ataxin 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2689889 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Target Information
Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenerative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus.
This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration, and other neurodegenerative characteristics.
The SCA7 gene encodes the ubiquitous 892-residue protein Ataxin-7, typically located in the cytoplasm and on the nuclear membrane of normal brain neurons.
In cells with SCA7 gene mutation, Ataxin 7 accumulates in intranuclear inclusions and can result in cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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