Thermo Fisher Scientific A2M Polyclonal Antibody
Thermo Fisher Scientific의 A2M Polyclonal Antibody는 인간, 생쥐, 랫트에 반응하며 Western blot에 적합합니다. 고순도(>95%) 항원 친화 크로마토그래피로 정제된 비결합형 항체로, 알츠하이머 병 등 연구용으로 활용됩니다. PBS/glycerol 완충액에 보관됩니다.
- 카탈로그번호
- PA586872
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human A2M |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803631 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Alpha 2-Macroglobulin (A2M) is an approximately 720-kDa homotetrameric glycoprotein composed of four identical ~180 kDa subunits.
A2M shares with other alpha-macroglobulins, such as complement components C3 and C4 and pregnancy zone protein (PZP), a broad ligand-binding capacity.
This enables alpha-macroglobulins to act as humoral defense barriers against foreign peptides in plasma.
A2M interacts and captures virtually any proteinase, functioning as a panprotease inhibitor.
In the brains of Alzheimer’s disease patients, A2M has been localized to diffuse amyloid plaques, supporting its important role in AD pathophysiology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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