Thermo Fisher Scientific CD354 (TREM-1) Monoclonal Antibody (TREM-37)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Flow Cytometry (Flow)

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

TREM-37

Immunogen

Recombinant human TREM-1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Storage conditions

4°C or -20°C if preferred

Shipping conditions

Wet ice

RRID

AB_2745178

Product Specific Information

Mouse anti Human Trem-1 antibody, clone TREM-37 recognizes Triggering receptor expressed on myeloid cells 1 also known as TREM-1, Triggering receptor expressed on monocytes 1 or CD354.

Target Information

TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. It is thought that TREM1 other related TREM proteins such as TREM2 act to modulate the inflammatory response. TREM1 has also been linked to inflammatory bowel disease resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.