Thermo Fisher Scientific Synaptophysin Monoclonal Antibody (7H12)
Synaptophysin 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC(P), ELISA에 적합합니다. Human, Mouse, Rat 시료에 반응하며 신경세포 말단 및 신경내분비 종양 연구에 활용됩니다. 장기 보관 시 -20°C 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7H12 |
| Immunogen | Purified recombinant fragment of SYP expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10986932 |
Product Specific Information
MA5-15623 antibody targets Synaptophysin (SYP) in indirect ELISA, IHC, and WB applications, showing reactivity with Human and Rat samples.
The immunogen is a purified recombinant fragment of SYP expressed in E. coli.
MA5-15623 detects SYP with a predicted molecular weight of approximately 33.8 kDa.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein located in presynaptic vesicles of nearly all neurons.
It has four transmembrane domains and forms a complex with dynamin under high calcium concentrations, suggesting a role in synaptic vesicle endocytosis.
Synaptophysin is involved in regulating short- and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the gene are associated with X-linked mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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