Thermo Fisher Scientific PTCH Polyclonal Antibody
PTCH 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot에 적합합니다. Mouse에 반응하며, Rat, Chicken, Human에도 교차 반응이 예상됩니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA123381
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues K(269) K I N Y Q V D S W E(279) of mouse PTCH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2253264 |
Product Specific Information
This antibody is expected to cross-react with rat, chicken, and human due to 100% sequence homology.
Target Information
This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in embryonic development and tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. The gene functions as a tumor suppressor, and its mutations are associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, and holoprosencephaly. Multiple transcript variants exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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