Thermo Fisher Scientific Rad23 Polyclonal Antibody
Rad23 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 효모 단백질 분석에 적합합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, 고순도의 Protein A 정제 항체입니다. DNA 손상 복구 연구용으로 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Yeast |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from Saccharomyces cerevisiae Rad23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV-damaged DNA. RAD23 resembles other DNA repair genes such as RAD2, RAD6, RAD7, RAD18, and RAD54, all of which show increased transcription in response to DNA damage and during meiosis. RAD23 encodes a nuclear protein containing a ubiquitin-like domain necessary for biological function. This domain affects protein function in a nonproteolytic manner. Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) and associates with the proteasome via its amino terminus. Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans. In addition to DNA repair in yeast, evidence suggests that Rad23 may regulate the activity of the 26S proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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