
Thermo Fisher Scientific COL1A2 Polyclonal Antibody
Human COL1A2 단백질을 인식하는 Rabbit Polyclonal Antibody. 면역세포화학(ICC/IF)에 사용 가능하며 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, PBS와 글리세롤 완충액에 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA584432
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COL1A2. Recombinant protein control fragment (Product # RP-106962) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791584 |
Product Specific Information
Immunogen sequence:
IKVYCDFSTG ETCIRAQPEN IPAKNWYRSS KDKKHVWLGE TINAGSQFEY NVEGVTSKEM ATQLAFMRLL ANYAS
Target Information
This gene encodes the pro-alpha2 chain of type I collagen, whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I collagen is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis, and tendon.
Mutations in this gene are associated with:
- Osteogenesis imperfecta types I–IV
- Ehlers-Danlos syndrome type VIIB
- Recessive Ehlers-Danlos syndrome Classical type
- Idiopathic osteoporosis
- Atypical Marfan syndrome
Symptoms associated with mutations in this gene tend to be less severe than those in COL1A1, reflecting the different roles of alpha2 chains in matrix integrity.
Three transcripts have been identified for this gene, resulting from alternate polyadenylation signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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