Thermo Fisher Scientific KAP3 Polyclonal Antibody
Thermo Fisher Scientific의 KAP3 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 고순도 항체로 Western blot, ICC/IF, IP에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific KAP3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Immunoprecipitation (IP) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human KAP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719897 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein with two activities on small G proteins including the Rho and Rap1 families and Ki-Ras: stimulating GDP/GTP exchange reactions and inhibiting membrane interactions.
The protein encoded by this gene contains nine Armadillo repeats and interacts with smg GDS through these repeats. It is concentrated around the endoplasmic reticulum and phosphorylated by v-src, which reduces its affinity for smg GDS.
This protein likely serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, playing a role in chromosome–ATPase motor protein interactions.
Several transcript variants encoding different isoforms have been identified for this gene.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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