Thermo Fisher Scientific GLUL/Glutamine Synthetase Polyclonal Antibody
GLUL/Glutamine Synthetase 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot 및 Immunoprecipitation에 사용 가능. Human에 반응하며 Mouse, Rat 등에서도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 항체.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 to 325 of human Glutamine synthetase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Bovine, and Dog.
Target Information
Glutamine synthetase (GS) is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthetase. Glutamate plays a central role in mammalian nitrogen flow, serving as both a nitrogen donor and acceptor. It also has an important role in regulating neurotransmitter glutamate metabolism.
Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activity and synthesis are highly regulated. GS activity is controlled by adenylylation and is decreased in the cerebral cortex of brains affected by Alzheimer’s disease, particularly near senile plaques, and under glucose deprivation conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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