Thermo Fisher Scientific GLUL/Glutamine Synthetase Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, and Pig

Target Information

Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays a central role in mammalian nitrogen flow, serving as both a nitrogen donor and acceptor. It also plays an important role in regulating neurotransmitter glutamate metabolism.
Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation and is decreased in the cerebral cortex of brains affected by Alzheimer’s disease, particularly near senile plaques. It is also reduced under glucose deprivation conditions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

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