Thermo Fisher Scientific Human PCBP4 Synthetic Peptide
인간 PCBP4 단백질의 카르복시 말단 17개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-20359의 블로킹 펩타이드로 사용 가능하며, 정제된 액상 형태로 제공됩니다. PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 함유. -20°C에서 보관.
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Thermo Fisher Scientific Human PCBP4 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human MCG10C.
PEP-0479 can be used as a blocking peptide with polyclonal antibody PA5-20359.
Target Information
MCG10 is a member of the KH-domain RNA-binding protein family. Proteins of this family, also referred to as alpha-CPs, bind to RNA with specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions.
MCG10 is induced by p53 and DNA damage via two p53-responsive promoter elements. Its overexpression in transfected cells results in suppression of cell proliferation by inducing apoptosis and cell cycle arrest in G2-M. Decreased expression of one isoform of MCG10 has been observed in many forms of lung cancer, suggesting that MCG10 may act as a tumor suppressor. Multiple alternatively spliced isoforms of MCG10 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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