Thermo Fisher Scientific ADAMTS13 Polyclonal Antibody, Agarose

Applications

Tested Dilution

Publications

Immunoprecipitation (IP)

30 - 50 µL gel slurry/100 µL of human serum

-

Product Specifications

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residues 75 and 125 of human ADAM (a disintegrin-like and metalloprotease) metallopeptidase with thrombospondin type 1 motif, 13. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ADAMTS13,uniProtId:Q76LX8-1,ncbiNodeId:9606,antigenRange:75-125,antigenLength:1427,antigenImageFileName:S301-000_ADAMTS13_Q76LX8-1_Goat.svg,antigenImageFileNamePDP:S301-000_ADAMTS13_Q76LX8-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Agarose Agarose Agarose

Form

Liquid

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.