ELK Biotechnology EAAT2 rabbit pAb
EAAT2 rabbit pAb는 흥분성 아미노산 수송체 2를 인식하는 폴리클로날 항체로, WB 분석에 적합합니다. 인간, 쥐, 생쥐 시료에서 반응하며, 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
EAAT2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Excitatory amino acid transporter 2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2) |
| Applications | WB |
| Recommended Dilutions | WB 1:1000–2000 |
| Immunogen | Synthetic Peptide of EAAT2 (AA range: 370–420) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 62 kD |
| GeneID (Human) | 6506 |
| Human Swiss-Prot No | P43004 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
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