ELK Biotechnology KCNK4 (TRAAK) rabbit pAb
KCNK4(TRAAK) 단백질을 인식하는 토끼 폴리클로날 항체로, 신경조직에서의 발현 연구에 적합합니다. IHC 및 IF에 사용 가능하며, 세포막 다중 통과 단백질 검출에 유용합니다. 고순도 IgG 형태, -20°C에서 1년 보관 가능합니다.
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제품명
KCNK4 (TRAAK) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | KCNK4; TRAAK; Potassium channel subfamily K member 4; TWIK-related arachidonic acid-stimulated potassium channel protein; Two pore potassium channel KT4.1; Two pore K(+) channel KT4.1 |
| Applications | IHC; IF |
| Recommended Dilutions | IHC 1:100–200 |
| Immunogen | Synthetic Peptide of KCNK4 (TRAAK), AA range: 38–88 |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 43 kD |
| GeneID (Human) | 50801 |
| Human Swiss-Prot No. | Q9NYG8 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature, and mechanical deformation of the lipid membrane. It is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene (GeneID: 106780802). [Provided by RefSeq, Nov 2015]
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