
ELK Biotechnology KVβ1 rabbit pAb
Voltage-gated potassium channel subunit beta-1에 대한 rabbit polyclonal antibody로, IHC 및 IF 실험에 적합합니다. 세포막 및 세포질에서 발현되는 단백질 검출에 유용하며, 인간, 생쥐, 랫트 시료에 반응합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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KVβ1 rabbit pAb
제품 개요
Voltage-gated potassium channel subunit beta-1 (Kvβ1)에 대한 rabbit polyclonal antibody로, 신경전달물질 방출, 심박수 조절, 인슐린 분비 등 다양한 생리적 기능 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | KVβ1 rabbit pAb |
| Alternative Names | Voltage-gated potassium channel subunit beta-1 (K(+) channel subunit beta-1; Kv-beta-1) |
| Applications | IHC; IF |
| Recommended Dilutions | IHC 1:100–200 |
| Immunogen | Synthetic Peptide of KVβ1 (AA range: 66–116) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| GeneID (Human) | 7881 |
| Human Swiss-Prot No | Q14722 |
| Species Reactivity | Human; Rat; Mouse |
| Cellular Localization | Cytoplasm; Membrane; Peripheral membrane protein (cytoplasmic side). Recruited to the cytoplasmic side of the cell membrane via interaction with pore-forming potassium channel alpha subunits. |
Background
Potassium channels are among the most complex voltage-gated ion channels, regulating diverse physiological processes such as neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume.
Four sequence-related potassium channel genes—shaker, shaw, shab, and shal—have been identified in Drosophila, each with human homologs.
This gene encodes a member of the voltage-gated, shaker-related potassium channel subfamily. It includes distinct isoforms encoded by alternatively spliced transcript variants, some of which serve as beta subunits forming heteromultimeric complexes with alpha subunits to modulate pore-forming channel activity.
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