ELK Biotechnology NM23A Rabbit rabbit pAb
NM23A Rabbit Polyclonal Antibody는 NME1 단백질을 인식하며 IHC 및 IF 실험에 적합합니다. 재조합 단백질을 면역원으로 사용하였고, 사람·쥐·마우스에 반응합니다. 세포질 및 핵에 위치하며 세포주기 의존적 핵 이동을 보입니다.
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NM23A Rabbit rabbit pAb
공급업체: ELK Biotechnology
대체명: NME1
제품 정보
| 항목 | 내용 |
|---|---|
| Applications | IHC; IF |
| Recommended Dilutions | IHC 1:100–200 |
| Immunogen | Recombinant Protein of NM23A of NME1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 4830 |
| Human Swiss-Prot No | P15531 |
| Species Reactivity | Human; Rat; Mouse |
| Storage | -20°C / 1 year |
| Sample Type | Rabbit |
세포 내 위치
Cytoplasm, Nucleus.
Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-Barr viral proteins or by degradation of the SET complex by GzmA.
배경 (Background)
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms.
Mutations in this gene have been identified in aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been found for this gene.
Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encode a fusion protein comprised of sequence sharing identity with each individual gene product.
[provided by RefSeq, Jul 2008]
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