ELK Biotechnology PI3 Kinase P85 Rabbit rabbit pAb
PI3 Kinase P85 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC 및 IF에 적합합니다. Recombinant Protein을 항원으로 제작되었으며, Human, Rat, Mouse에 반응합니다. 세포 내 다양한 위치에서 PI3K 신호전달 연구에 활용됩니다.
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PI3 Kinase P85 Rabbit rabbit pAb
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ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | PIK3R1 |
| Applications | IHC; IF |
| Recommended Dilutions | IHC 1:100–200 |
| Immunogen | Recombinant Protein of PI3 Kinase P85 of PIK3R1 |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 85 kD |
| GeneID (Human) | 5295 |
| Human Swiss-Prot No | P27986 |
| Cellular Localization | nucleus, cytoplasm, cis-Golgi network, cytosol, plasma membrane, cell-cell junction, phosphatidylinositol 3-kinase complex (class IA), membrane, perinuclear endoplasmic reticulum membrane |
| Species Reactivity | Human; Rat; Mouse |
Background
Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and mutations in this gene have been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. (RefSeq, Jun 2011)
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