ELK Biotechnology α-tubulin rabbit pAb
α-tubulin rabbit pAb은 세포골격 연구용 폴리클로날 항체로, 인간·마우스·랫트 반응성을 보입니다. WB에 최적화되어 있으며, α-tubulin 단백질 검출에 적합합니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology α-tubulin rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | α-tubulin rabbit pAb |
| Alternative Names | YM3217 |
| Applications | WB |
| Recommended Dilutions | WB: 1:2000 |
| Immunogen | Recombinant Protein of Tubulin alpha-1A chain |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 52 kD |
| GeneID (Human) | 7846 / 10376 |
| Human Swiss-Prot No | Q71U36 / P68363 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human, Mouse, Rat |
Background
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta, and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly.
There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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