
ELK Biotechnology Histone H2A.X (Phospho Tyr142) rabbit pAb
Histone H2A.X (Phospho Tyr142)에 특이적인 rabbit polyclonal antibody로, 핵 내 히스톤 단백질 인산화 연구에 적합합니다. WB 실험에 사용 가능하며, 고감도 검출과 안정적 저장(-20°C, 1년)을 제공합니다.
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Histone H2A.X (Phospho Tyr142) rabbit pAb
제품 개요
Histone H2A.X (Phospho Tyr142)에 특이적인 rabbit polyclonal antibody로, 핵 내 히스톤 단백질의 인산화 상태를 검출하는 데 사용됩니다.
이 항체는 합성 펩타이드 면역원으로 제작되었으며, Western blot(WB) 분석에 최적화되어 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2A.X (Phospho Tyr142) rabbit pAb |
| Alternative Names | H2AFX; H2AX; Histone H2A.x; H2a/x |
| Applications | WB |
| Recommended Dilutions | WB: 1:1000–2000 |
| Immunogen | Synthetic Peptide of Histone H2A.X (Phospho Tyr142) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15 kD |
| GeneID (Human) | 3014 |
| Human Swiss-Prot No | P16104 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
배경 정보
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes.
Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction into higher-order structures.
This gene encodes a replication-independent histone that is a member of the histone H2A family and generates two transcripts through the use of the conserved stem-loop termination motif and the polyA addition motif.
[Provided by RefSeq, Oct 2015]
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