ELK Biotechnology Histone H3 (Phospho Thr45) rabbit pAb
Histone H3 (Phospho Thr45) 인산화 부위를 인식하는 rabbit polyclonal antibody. WB에 적합하며, 인간·마우스·랫트 시료에서 반응. 합성 펩타이드 면역원 사용, 핵 및 염색체에 위치한 히스톤 단백질 검출에 유용.
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Histone H3 (Phospho Thr45) rabbit pAb
제품 개요
Histone H3 (Phospho Thr45)를 인식하는 rabbit polyclonal antibody로, 주로 Western blot(WB) 분석에 사용됩니다. 히스톤 H3 단백질의 인산화 상태를 검출하며, 인간, 마우스, 랫트 시료에서 반응합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Phospho Thr45) rabbit pAb |
| Alternative Names | HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3 |
| Applications | WB |
| Recommended Dilutions | WB: 1:1000 |
| Immunogen | Synthetic Peptide of Histone H3 (Phospho Thr45) |
| Host | Rabbit |
| Storage Conditions | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15–17 kDa |
| Gene ID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 |
| Human Swiss-Prot No. | P68431 / Q71DI3 / P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone (H1) with the DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead containing a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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