ELK Biotechnology Histone H1 (Tri Methyl Lys25) rabbit pAb
Histone H1 (Tri Methyl Lys25)에 특이적인 토끼 폴리클로날 항체로, 핵 내 유크로마틴에서의 히스톤 변형 연구에 적합합니다. WB에서 사용 가능하며, 1:1000~2000 희석 권장. -20°C에서 1년 보관 가능합니다.
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Histone H1 (Tri Methyl Lys25) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H1 (Tri Methyl Lys25) rabbit pAb |
| Alternative Names | H1K25ME3; HIST1H1A; H1F1; Histone H1.1; Histone H1a; HIST1H1C; H1F2; Histone H1.2; Histone H1c; Histone H1d; Histone H1s-1; HIST1H1D; H1F3; Histone H1.3; Histone H1c; Histone H1s-2; HIST1H1E; H1F4; Histone H1.4; Histone H1b; Histone H1s-4 |
| Applications | WB |
| Recommended Dilutions | WB: 1:1000–2000 |
| Immunogen | Synthetic Peptide of Histone H1 (Tri Methyl Lys25) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 17–25 kD |
| GeneID (Human) | 3024 / 3006 / 3007 / 3008 |
| Human Swiss-Prot No. | Q02539 / P16403 / P16402 / P10412 |
| Cellular Localization | Nucleus, Chromosome, Mainly localizes in euchromatin |
| Species Reactivity | Human |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes.
The linker histone H1 interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher-order structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6. (RefSeq, Aug 2015)
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