ELK Biotechnology Histone H3 (Di Methyl Lys36) rabbit pAb
Histone H3 (Di Methyl Lys36) rabbit polyclonal antibody로, H3K36me2 변형을 인식합니다. Western blot에 적합하며, 인체·마우스·랫트 시료에서 반응합니다. 합성 펩타이드를 면역원으로 제작되었으며, 핵 및 염색체 단백질 연구에 유용합니다.
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제품명
Histone H3 (Di Methyl Lys36) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | H3K36ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; H3F3A; H3F3B; H3.3A; H3.3B; Histone H3.1; Histone H3.2; Histone H3.3 등 |
| Applications | WB |
| Recommended Dilutions | WB: 1:500–1:1000 |
| Immunogen | Synthetic Peptide of Histone H3 (Di Methyl Lys36) |
| Storage | -20°C, 1년 보관 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15–17 kDa |
| Gene ID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 |
| Human Swiss-Prot No. | P68431 / Q71DI3 / P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Each nucleosome consists of approximately 146 bp of DNA wrapped around an octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone belonging to the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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