ELK Biotechnology Histone H3 (Tri Methyl Lys18) rabbit pAb
Histone H3 (Tri Methyl Lys18) rabbit polyclonal antibody로, 인간 및 마우스 시료에서 사용 가능. Western blot에 적합하며, 고순도 합성 펩타이드 면역원으로 제작. 핵 내 히스톤 구조 연구 및 크로마틴 조절 기전 분석에 유용.
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Histone H3 (Tri Methyl Lys18) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H3 (Tri Methyl Lys18) rabbit pAb |
| Alternative Names | H3K18ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3 |
| Applications | WB |
| Recommended Dilutions | WB: 1:500–1000 |
| Immunogen | Synthetic Peptide of Histone H3 (Tri Methyl Lys18) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15–17 kD |
| GeneID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 |
| Human Swiss-Prot No | P68431 / Q71DI3 / P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of linker histone H1 with DNA between nucleosomes to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails and contain a palindromic termination element. It is located in the large histone gene cluster on chromosome 6p22-p21.3. (RefSeq, Aug 2015)
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