ELK Biotechnology Histone H3 (Tri Methyl Lys27) rabbit pAb
Histone H3 (Tri Methyl Lys27) rabbit polyclonal antibody로, H3K27me3 표지를 인식합니다. WB에 적합하며 1:500–1000 희석 권장. 인간, 마우스, 랫트 시료에 반응하며, 핵 및 염색체에 위치한 히스톤 H3 단백질 연구에 사용됩니다.
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Histone H3 (Tri Methyl Lys27) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product Name | Histone H3 (Tri Methyl Lys27) rabbit pAb |
| Alternative Names | H3K27ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3 |
| Applications | WB |
| Recommended Dilutions | WB: 1:500–1000 |
| Immunogen | Synthetic Peptide of Histone H3 (Tri Methyl Lys27) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15–17 kD |
| Gene ID (Human) | 8350 / 8351 / 8352 / 8353 / 8354 / 8355 / 8356 / 8357 / 8358 / 8968 |
| Human Swiss-Prot No. | P68431 / Q71DI3 / P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction with linker histone H1, forming higher-order chromatin structures. This gene, part of the histone H3 family, is intronless and encodes a replication-dependent histone. Its transcripts lack polyA tails and contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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