
ELK Biotechnology Histone H3 (Tri Methyl Lys4) rabbit pAb
Histone H3 (Tri Methyl Lys4) rabbit polyclonal antibody for WB detection of H3K4me3 modification. Recognizes nuclear histone H3 variants in human, mouse, and rat. High specificity with synthetic peptide immunogen and stable storage at -20°C for 1 year.
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Histone H3 (Tri Methyl Lys4) rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Product Name | Histone H3 (Tri Methyl Lys4) rabbit pAb |
| Alternative Names | H3K4ME3; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; HIST2H3A; HIST2H3C; H3F2; H3FM; HIST2H3D; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3 |
| Applications | WB |
| Recommended Dilutions | WB: 1:500–1000 |
| Immunogen | Synthetic Peptide of Histone H3 (Tri Methyl Lys4) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15–17 kD |
| GeneID (Human) | 8350, 8351, 8352, 8353, 8354, 8355, 8356, 8357, 8358, 8968 |
| Human Swiss-Prot No | P68431, Q71DI3, P84243 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of eukaryotic chromosomal fibers. Each nucleosome consists of approximately 146 bp of DNA wrapped around an octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through interaction with linker histone H1 to form higher-order chromatin structures.
This gene is intronless and encodes a replication-dependent histone belonging to the histone H3 family. Transcripts lack polyA tails and contain a palindromic termination element. The gene is located in the large histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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