ELK Biotechnology Histone H4 (Di Methyl Lys79) rabbit pAb
Histone H4 (Di Methyl Lys79) rabbit polyclonal antibody for WB applications. Recognizes H4K79ME2 modification in human, mouse, and rat samples. Synthetic peptide immunogen, stored at -20°C for 1 year. Provides strong nuclear localization specificity.
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Histone H4 (Di Methyl Lys79) rabbit pAb
제품 개요
Histone H4 (Di Methyl Lys79) rabbit polyclonal antibody는 히스톤 H4의 Lys79 이중 메틸화 변형을 인식하는 항체로, 웨스턴 블롯(WB) 분석에 적합합니다. 핵 및 염색체 수준에서 특이적 결합을 보여줍니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H4 (Di Methyl Lys79) rabbit pAb |
| Alternative Names | H4K79ME2; HIST1H4A; H4/A; H4FA; HIST1H4B; H4/I; H4FI; HIST1H4C; H4/G; H4FG; HIST1H4D; H4/B; H4FB; HIST1H4E; H4/J; H4FJ; HIST1H4F; H4/C; H4FC; HIST1H4H; H4/H; H4FH; HIST1H4I; H4/M; H4FM; HIST1H4J; H4/E; H4FE; HIST1H4K; H4/D; H4FD; HIST1H4L; H4/K; H4FK; HIST2H4A; H4/N; H4F2; H4FN; HIST2H4; HIST2H4B; H4/O; H4FO; HIST4H4; Histone H4 |
| Applications | WB |
| Recommended Dilutions | WB: 1:500–1000 |
| Immunogen | Synthetic Peptide of Histone H4 (Di Methyl Lys79) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 14 kD |
| GeneID (Human) | 121504 |
| Human Swiss-Prot No | P62805 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of H2A, H2B, H3, and H4 form an octamer around which approximately 146 bp of DNA is wrapped, forming nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction. This gene is intronless and encodes a replication-dependent histone H4 family member. Transcripts lack polyA tails and instead contain a palindromic termination element. The gene is located in the histone microcluster on chromosome 6p21.33. (RefSeq, Aug 2015)
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