
ELK Biotechnology Histone H2A.X (Acetyl Lys5) rabbit pAb
Histone H2A.X (Acetyl Lys5) rabbit polyclonal antibody for WB applications. Recognizes acetylated Lys5 of H2A.X in human, mouse, and rat samples. Provides reliable nuclear localization detection with high specificity and stability at -20°C for 1 year.
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Histone H2A.X (Acetyl Lys5) rabbit pAb
제품 개요
Histone H2A.X (Acetyl Lys5) rabbit polyclonal antibody는 히스톤 H2A.X의 Lys5 아세틸화를 특이적으로 인식합니다. 핵 및 염색체 수준에서의 단백질 위치 확인에 유용하며, Western blot(WB) 분석에 최적화되어 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2A.X (Acetyl Lys5) rabbit pAb |
| Alternative Names | H2AFX; H2AX; Histone H2A.x; H2a/x |
| Applications | WB |
| Recommended Dilutions | WB: 1:1000–2000 |
| Immunogen | Synthetic Peptide of Histone H2A.X (Acetyl Lys5) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Observed Band | 15 kD |
| GeneID (Human) | 3014 |
| Human Swiss-Prot No | P16104 |
| Cellular Localization | Nucleus; Chromosome |
| Species Reactivity | Human; Mouse; Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer around which approximately 146 bp of DNA is wrapped in repeating units called nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and functions in chromatin compaction. The H2A.X gene encodes a replication-independent histone that is a member of the H2A family and produces two transcripts through distinct termination motifs.
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