
ELK Biotechnology CXCL2 rabbit pAb
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Product name: | CXCL2 rabbit pAb |
Alternative Names: | C-X-C motif chemokine 2 (Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha) [Cleaved into: GRO-beta(5-73;GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353)] |
Applications: | WB; ELISA |
Recommended Dilutions: | WB 1:1000-2000 ELISA 1:5000-20000 |
Immunogen: | Synthesized peptide derived from human GROβ AA range: 58-107 |
Storage: | Rabbit |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
GeneID(Human): | 2920 |
Human Swiss-Prot No: | P19875 |
Cellular localization: | Secreted. |
Background: | function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family., |
Species Reactivity: | Human;Rat;Mouse; |
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