ELK Biotechnology MAX (Phospho Ser11) rabbit pAb
인간 MAX 단백질의 인산화 Ser11 부위를 인식하는 rabbit polyclonal antibody로, WB 및 ELISA에 적합합니다. 핵 및 수상돌기에서의 세포 내 위치를 연구할 수 있으며, 고순도 IgG 형태로 -20°C에서 1년간 보관 가능합니다.
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제품명
MAX (Phospho Ser11) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Protein max (Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human MAX (Phospho Ser11) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 4149 |
| Human Swiss-Prot No | P61244 |
| Cellular Localization | Nucleus; Cell projection, dendrite |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It can form homodimers and heterodimers with other family members such as Mad, Mxi1, and Myc. Myc is an oncoprotein involved in cell proliferation, differentiation, and apoptosis. These dimers compete for a common DNA target site (E box), providing a complex system of transcriptional regulation. Mutations in this gene have been associated with hereditary pheochromocytoma. A pseudogene is located on chromosome 7, and alternative splicing results in multiple transcript variants. [RefSeq, Aug 2012]
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