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ELK Biotechnology NFAT1 (Phospho Ser326) rabbit pAb
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NFAT1 (Phospho Ser326) rabbit pAb는 인산화된 NFAT1 단백질을 인식하는 폴리클로날 항체로, WB, ELISA, IHC에 사용됩니다. 사람, 생쥐, 랫트에 반응하며 세포 내 NFAT 신호전달 연구에 적합합니다. 고순도 IgG로 -20°C에서 1년 보관 가능합니다.
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- pk
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ELK Biotechnology ES20145-100UL NFAT1 (Phospho Ser326) rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES20145-50UL NFAT1 (Phospho Ser326) rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology NFAT1 (Phospho Ser326) rabbit pAb
제품명
NFAT1 (Phospho Ser326) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2; NFATc2; NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1) |
| Applications | WB; ELISA; IHC |
| Recommended Dilutions | WB 1:500–2000; IHC-p 1:50–300; ELISA 1:2000–20000 |
| Immunogen | Synthesized peptide derived from human NFAT1 (Phospho Ser326) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 100 kDa |
| Gene ID (Human) | 4773 |
| Human Swiss-Prot No. | Q13469 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Cytoplasm and nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to help cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in regulating gene transcription. |
Background
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein containing a REL-homology region (RHR) and an NFAT-homology region (NHR). It is present in the cytosol and translocates to the nucleus upon T cell receptor (TCR) stimulation, forming part of the NFAT transcription complex that regulates gene expression during immune responses. Alternative splicing variants encoding different isoforms have been identified. [RefSeq, Apr 2012]
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