ELK Biotechnology Histone H2A (Acetyl Lys119) rabbit pAb
Histone H2A (Acetyl Lys119) rabbit polyclonal antibody로, 인간, 마우스, 랫트 시료에 반응합니다. WB 및 ELISA에 사용 가능하며, 고순도 IgG로 1 mg/ml 농도 제공. 핵 내 히스톤 단백질 인산화 연구에 적합.
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Histone H2A (Acetyl Lys119) rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Histone H2A (Acetyl Lys119) rabbit pAb |
| Alternative Names | Histone H2A type 1 (H2A.1; Histone H2A/p) |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:1000–2000, ELISA 1:5000–20000 |
| Immunogen | Synthesized peptide derived from human Histone H2A (Acetyl Lys119) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kD |
| GeneID (Human) | 8329 |
| Human Swiss-Prot No | P0C0S8 / P16104 |
| Cellular Localization | Nucleus, Chromosome |
| Species Reactivity | Human, Mouse, Rat |
Background
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Two molecules each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped to form nucleosomes. The linker histone H1 interacts with linker DNA between nucleosomes and contributes to chromatin compaction into higher-order structures.
This gene is intronless and encodes a replication-dependent histone belonging to the histone H2A family. Transcripts from this gene lack polyA tails but contain a palindromic termination element. The gene is located in the small histone gene cluster on chromosome 6p22–p21.3. (RefSeq, Aug 2015)
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