Thermo Fisher Scientific Perilipin A Polyclonal Antibody
Thermo Fisher Scientific의 Perilipin A Polyclonal Antibody는 인간, 생쥐, 랫트 시료에 반응하며 Western blot, IHC, ICC/IF, ELISA 등에 적합합니다. KLH 결합 합성 펩타이드(aa 85-180)를 면역원으로 사용한 Rabbit IgG 형의 비결합 항체로, 고순도 Protein A 정제 및 안정한 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Perilipin A, amino acids 85–180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adipose tissue serves as an energy reserve and is tightly regulated. Adipocytes secrete important proteins such as lipoprotein lipase (LPL), leptin, Acrp30, resistin, and perilipin.
Perilipin is an intracellular lipid droplet protein that is hormonally regulated and localized to lipid droplet surfaces. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A and modulates hormone-sensitive lipase (HSL) activity, which hydrolyzes triacylglycerol.
Perilipin expression is restricted to adipocytes and steroidogenic cells. Two isoforms, Perilipin A and B, are known and result from differential splicing of a single-copy gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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