
Thermo Fisher Scientific CD1a/Cortical thymocyte antigen CD1A Polyclonal Antibody
Thermo Fisher Scientific의 CD1a 폴리클로날 항체는 인간 CD1a 단백질을 인식하며 IHC, ICC/IF, Flow Cytometry, ELISA 등에 사용됩니다. 고순도 Protein A 정제 항체로 다양한 조직의 CD1a 발현 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:300 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CD1a, amino acids 151–250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD1a is a non-polymorphic MHC Class I-related cell surface glycoprotein expressed in association with Beta 2 microglobulin. It is found on cortical thymocytes, Langerhans cells, and interdigitating cells, as well as in certain T-cell malignancies and histiocytosis X.
CD1a proteins mediate lipid and glycolipid antigen presentation to T cells and form heterodimers with beta-2-microglobulin. The CD1 gene family (CD1a–e) is located on chromosome 1 and exhibits distinct localization and ligand specificity. CD1a localizes to the plasma membrane and early endocytic vesicles. Alternative splicing variants have been observed but their biological significance remains unclear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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