Thermo Fisher Scientific Human FOXRED2 Synthetic Peptide
인간 FOXRED2 단백질의 N-말단 17개 아미노산에 해당하는 합성 펩타이드. 항체 PA5-34345의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2) 및 0.1% BSA 용액에 200 µg/mL 농도로 제공. -20°C에서 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human FOXRED2.
PEP-1388 can be used as a blocking peptide with polyclonal antibody PA5-34345.
Target Information
FOXRED2, also known as ERFAD, is an endoplasmic reticulum (ER) luminal flavoprotein which may function in ER-associated degradation (ERAD). It is proposed to bind non-native proteins in the ER and target them to the ubiquitination machinery for degradation. Knockdown of FOXRED2 delays degradation of the ERAD model substrate ribophorin 332 and decreases polyubiquitinated protein levels. Defects in the related protein FOXRED1 cause mitochondrial complex I deficiency (MT-C1D), suggesting FOXRED2 may also play a role in MT-C1D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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