Thermo Fisher Scientific MSX1/MSX2 Polyclonal Antibody
MSX1/MSX2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 Immunocytochemistry에 적합하며, 인간·마우스·랫트 시료에서 반응. 친화 크로마토그래피로 정제된 액상 제품으로, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MSX1 (Accession P28360), corresponding to amino acid residues W145–Q195. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852649 |
Product Specific Information
Antibody detects endogenous levels of total MSX1/2.
Target Information
Drosophila muscle segment (msh) homolog 1, a homeo domain encoding gene that inhibits MYOD1 expression. Highly expressed in dental mesenchyme during the critical bud stage, involved in epithelial-mesenchymal signaling in multiple organs, and associated with cleft lip and palate pathogenesis. Interacts with MSX2 in mouse limb bud patterning.
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also play roles in limb pattern formation, craniofacial development (particularly odontogenesis), and tumor growth inhibition.
Tissue specificity: Expressed in the developing nail bed mesenchyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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