Thermo Fisher Scientific CD52 Polyclonal Antibody
CD52 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot 및 IHC(P) 적용 가능. 인간 및 비인간 영장류 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로 면역세포 표지 및 질환 연구에 적합.
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Applications
- Western Blot (WB): 1:1,000–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD52 (Accession P31358), corresponding to amino acid residues L5–I55 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2852648 |
Product Specific Information
Antibody detects endogenous levels of total CD52.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It plays a role in immune response regulation and is a potential therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody used to treat these conditions by depleting CD52-expressing immune cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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