Thermo Fisher Scientific PIM2 Polyclonal Antibody
PIM2 단백질을 인식하는 염소 유래 폴리클로날 항체로, Western blot, IHC, ICC, Flow cytometry 등에 사용 가능. 인간 단백질에 반응하며 TBS 버퍼 내 액상 형태로 제공. 암 연구 및 세포 신호전달 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QTPAEDVPLNPSK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933366 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
PIM2 is a proto-oncogene that phosphorylates BAD, partially inhibiting its apoptotic function. PIM proteins (PIM-1, PIM-2, and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to PIM-1 with similar oncogenic functions. It is abundantly expressed in hematopoietic tissues, spleen, thymus, peripheral blood leukocytes, testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion, and elevated levels have been observed in certain cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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