Thermo Fisher Scientific ANPEP Monoclonal Antibody (1G1)
인간 ANPEP(CD13)을 인식하는 Mouse monoclonal antibody (Clone 1G1). ELISA에 최적화되어 있으며, 비결합형 액상 형태로 제공. 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4)에 보존제 없이 저장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Application: ELISA
- Tested Dilution: 0.1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G1 |
| Immunogen | ANPEP (AAH58928.1, 858 a.a. ~ 967 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
DATSTIISIT NNVIGQGLVW DFVQSNWKKL FNDYGGGSFS FSNLIQAVTR RFSTEYELQQ LEQFKKDNEE TGFGSGTRAL EQALEKTKAN IKWVKENKEV VLQWFTENSK
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types.
It functions as a metalloprotease that removes neutral amino acids from small peptides, thereby modulating bioactive peptide activity.
CD13 plays roles in:
- Extracellular matrix degradation
- Antigen processing and signal transduction
- Inflammatory response regulation
- Cell motility, intercellular contact, and vascularization
CD13 is expressed by granulocytes, monocytes, and myeloid leukemia cells.
Its expression is associated with protection of leukemic cells against apoptosis and poor prognosis in carcinomas.
Additionally, CD13 acts as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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