Thermo Fisher Scientific CYP1A2 Recombinant Rabbit Monoclonal Antibody (8B2)
사람 CYP1A2 단백질을 인식하는 재조합 토끼 단클론 항체입니다. Western blot과 IHC(Paraffin)에서 검증되었습니다. HEK293 세포에서 발현되었으며, 비접합형 액상 포맷으로 제공됩니다. 약물 대사 연구 및 효소 발현 분석에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8B2 |
| Immunogen | A synthesized peptide derived from human Cytochrome P450 1A2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898217 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. The encoded protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. Although the enzyme’s endogenous substrate is unknown, it can metabolize certain PAHs to carcinogenic intermediates. Other xenobiotic substrates include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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