Thermo Fisher Scientific FGR Polyclonal Antibody

Applications

• Western Blot (WB): 0.1–0.5 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways, including the integrin pathway and downstream of chemokine and cytokine receptors. This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively.
It localizes to plasma membrane ruffles and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.