Thermo Fisher Scientific HIP1 Polyclonal Antibody
HIP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 유래 폴리클로날 항체. Western blot에 적합하며 인간 및 생쥐 시료 반응. 항원 친화 크로마토그래피로 정제되어 고순도 확보. 신경퇴행성 및 암 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human HIP1 (UniProt ID: O00291-1, Antigen range: 1–1037) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720792 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Huntingtin disease, a neurodegenerative disorder, is caused by the expansion of a polymorphic glutamine tract in huntingtin. Huntingtin Interacting Protein 1 (HIP1) is a proapoptotic, cargo-specific adaptor protein implicated in the pathogenesis of Huntington’s disease. HIP1 is also involved in clathrin coat recruitment to lipid membranes and may contribute to tumorigenesis by promoting the survival of precancerous and cancerous cells. Its expression is significantly associated with prostate and colon cancer metastasis, making it a potential prognostic marker for these cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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