Thermo Fisher Scientific IL1RAPL1 Polyclonal Antibody
IL1RAPL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human IL1RAPL1, amino acids 301–400 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The IL1RAPL1 protein is a member of the interleukin 1 receptor family, similar to interleukin 1 accessory proteins. It contains an N-terminal signal peptide, three extracellular Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail that interacts with multiple signaling molecules.
This gene is located on chromosome X and is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations have been observed in affected patients. IL1RAPL1 is highly expressed in postnatal brain regions involved in the hippocampal memory system, suggesting a role in memory and learning processes, as well as synapse formation and stabilization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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