Thermo Fisher Scientific APLP1 Polyclonal Antibody
인간 APLP1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 신경세포 발달 및 APP 관련 연구에 적합.
- 카탈로그번호
- PA556021
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human APLP1. Recombinant protein control fragment (Product # RP-94786) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2638075 |
Product Specific Information
Immunogen sequence:
GTAVGDPSTR SWPPGSRVEG AEDEEEEESF PQPVDDYFVE PPQAEEEEET VPPPSSHTLA VVGKVTPTPR PTDGVDIYFG MPGEISEHEG FLRAKMDLEE RRMRQINEVM REWAMADNQS K
Antigen sequence identity:
- Mouse: 83%
- Rat: 85%
Target Information
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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