Thermo Fisher Scientific APLP1 Polyclonal Antibody
Human APLP1 단백질에 특이적인 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 분석에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 4°C 또는 -20°C에서 안정적 보관 가능. 연구용으로만 사용.
- 카탈로그번호
- PA556020
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific APLP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human APLP1. Recombinant protein control fragment (Product #RP-102552) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638074 |
Product Specific Information
Immunogen sequence:
HLAQELRPQI QELLHSEHLG PSELEAPAPG GSSEDKGGLQ PPDSKDDTPM TLPKGSTEQD AASPEKEKMN PLEQYERKVN ASVPRGFPFH SSEIQRDELA PAGTGVSLGA PHR
Highest antigen sequence identity to orthologs:
- Mouse: 74%
- Rat: 70%
Target Information
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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