Thermo Fisher Scientific Human RET, GST Tag Recombinant Protein
인간 RET 단백질을 GST 태그로 융합한 재조합 단백질로, 키나아제 활성 분석에 적합합니다. 곤충 세포에서 발현되며 정제된 액상 형태입니다. 세포 성장 및 분화 신호전달 연구에 활용됩니다. -80°C 보관, 동결/해동 반복 방지 필요.
- 카탈로그번호
- PR7355A
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human RET, GST Tag Recombinant Protein
Thermo Fisher Scientific Human RET, GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 658–1114 |
| Tag | GST-tag |
| Molecular Weight | 79 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris-HCl (pH 7.5), 50% glycerol, 0.02% Triton X-100, 150 mM NaCl, 0.5 mM EDTA, 2 mM DTT |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use original packaging until exhausted.
- For larger sizes, reduce freeze/thaw cycles by preparing aliquots (not below 20 µL).
- Never store kinase diluted.
- Properly stored at -80°C, product guaranteed for 6 months from date of purchase.
- Protein Form: Cytoplasmic
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia types IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional variants have been described but not biologically confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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